Brain training reached a turning point in 2025, after years of growing evidence snowballed into an avalanche of scientific proof. A surge of new research about BrainHQ helped erode long-standing skepticism, with a record-breaking 70 peer-reviewed publications in science and medical journals in 2025.
These studies reported on BrainHQ’s impact on cognition, psychological resilience, physical health, biochemical brain health, and more.
“Thousands of scientists were involved in designing, testing, and validating the exercises and assessments in BrainHQ over the past two decades,” said Dr. Henry Mahncke, CEO of Posit Science. “What’s different now is the scale. The evidence has grown so large that independent reviews are increasingly reaching the same conclusion: these exercises work.”
Some highlights from 2025’s studies
The studies completed in 2025 cover a wide range of benefits. A few of the highlights include:
- A comprehensive and systematic review of mobile cognitive training apps that gave BrainHQ the top score of all apps surveyed.
- A groundbreaking brain imaging study that showed BrainHQ training turns back the clock on brain chemistry by about 10 years.
- A large study sponsored by the Alzheimer’s Association that found significant improvement in global cognition when people used BrainHQ, followed a modified Mediterranean diet, and did physical exercise.
- A study among active-duty military that showed BrainHQ improved multiple measures of cognitive resilience.
Your brain health matters!
BrainHQ rewires the brain so you can think faster, focus better, and remember more. And that helps people feel happier, healthier, and more in control. Sign up today!
New assessment studies
Along with brain training, the BrainHQ team has recently developed and validated dozens of assessments that help monitor brain health and function. What’s particularly important is that these assessments are short (often just a few minutes long) and easy-to-use on a computer or mobile device. That makes assessing cognitive status much more accessible for clinicians, researchers, and other medical professionals. In 2025, six studies of BrainHQ assessments were published, including:
- A breakthrough study showing that the BrainHQ team has successfully built the first short, online digital assessment that can provide a quick scientific estimate of acetylcholine levels, without the need for the special expertise, materials, and imaging equipment. (Acetylcholine is an important brain chemical related to the ability to pay attention.)
- A study that confirmed a BrainHQ assessment provides a valid scientific measure of cognitive skills older adults need to live independently.
- A study among long-haul truck drivers showed assessment results corresponded with findings from a much longer assessment in a driving simulator.
Adding it all up
The 70 papers published in 2025 build on years of scientific work. To date, more than 300 studies have shown that BrainHQ brings real benefits to people who use the program. Such benefits include improvements in cognition (attention, processing speed, memory, and decision-making), in quality of life (happiness, confidence, and health) and in real-world activities (balance, driving, independent living, and workplace activities).
The proof is now unequivocal: BrainHQ is the leader in cognitive training, and it works like no other program.
Your brain health matters!
BrainHQ rewires the brain so you can think faster, focus better, and remember more. And that helps people feel happier, healthier, and more in control. Sign up today!
