Mild Cognitive Impairment (MCI)

Carvalho, Cíntia Monteiro, Bruno Costa Poltronieri, Karin Reuwsaat, Maria Eduarda Alves Reis, and Rogerio Panizzutti. 2025. “Digital Cognitive Training for Functionality in Mild Cognitive Impairment: A Randomized Controlled Clinical Trial.” GeroScience, January. https://doi.org/10.1007/s11357-024-01464-x.
Macchiarelli, Justin E, Courtney Dowell-Esquivel, Alejandro Martinez, Andrea Rivera-Molina, Annalee Mueller, Peter Kallestrup, Sara J. Czaja, and Philip D. Harvey. 2024. “Association of Racial Status and Training Language with Baseline Performance and Training Gains During Computerized Training of Technology-Related Everyday Functional Skills In Older Adults.” The American Journal of Geriatric Psychiatry: Open Science, Education, and Practice. https://doi.org/10.1016/j.osep.2024.07.004.
Harvey, Philip D., Courtney Dowell-Esquivel, Justin E. Macchiarelli, Alejandro Martinez, Peter Kallestrup, and Sara J. Czaja. 2024. “Early Prediction of Mastery of a Computerized Functional Skills Training Program in Participants with Mild Cognitive Impairment.” International Psychogeriatrics, 1–12. https://doi.org/10.1017/S1041610224000115.
McMaster, M., S. Kim, L. Clare, S. J. Torres, N. Cherbuin, and K. J. Anstey. 2023. “The Feasibility of a Multidomain Dementia Risk Reduction Randomised Controlled Trial for People Experiencing Cognitive Decline: The Body, Brain, Life for Cognitive Decline (BBL-CD).” Aging & Mental Health, 1–9. https://doi.org/10.1080/13607863.2023.2190083.
Chwa, Won Jong, Cyrus A. Raji, Kat Toups, Ann Hathaway, Deborah Gordon, Henrianna Chung, Alan Boyd, et al. 2023. “Longitudinal White and Gray Matter Response to Precision Medicine-Guided Intervention for Alzheimer’s Disease.” Journal of Alzheimer’s Disease: JAD 96 (3): 1051–58. https://doi.org/10.3233/JAD-230481.
Chuang, I-Ching, Hui-Yan Chiau, Wan-Wen Liao, Yih-Ru Wu, Chih-Hung Chang, and Ching-Yi Wu. 2023. “Effects of Computer-Based Cognitive Training Combined with Physical Training for Older Adults with Cognitive Impairment: A Four-Arm Randomized Controlled Trial.” Digital Health 9. https://doi.org/10.1177/20552076231203633.
Toups, Kat, Ann Hathaway, Deborah Gordon, Henrianna Chung, Cyrus Raji, Alan Boyd, Benjamin D. Hill, et al. 2022. “Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project.” Journal of Alzheimer’s Disease 88:1411–21. https://doi.org/10.3233/JAD-215707.
Levy, Shellie-Anne, Glenn Smith, Liselotte De Wit, Brittany DeFeis, Gelan Ying, Priscilla Amofa, Dona Locke, et al. 2022. “Behavioral Interventions in Mild Cognitive Impairment (MCI): Lessons from a Multicomponent Program.” Neurotherapeutics 19 (1): 117–31. https://doi.org/10.1007/s13311-022-01225-8.
Harvey, Philip D., Matthew Zayas-Bazan, Lize Tibiriçá, Peter Kallestrup, and Sara J. Czaja. 2022. “Improvements in Cognitive Performance With Computerized Training in Older People With and Without Cognitive Impairment: Synergistic Effects of Skills-Focused and Cognitive-Focused Strategies.” The American Journal of Geriatric Psychiatry 30 (6): 717–26. https://doi.org/10.1016/j.jagp.2021.11.008.
Chen, Quanjing, Adam Turnbull, Martin Cole, Zhengwu Zhang, and Feng V. Lin. 2022. “Enhancing Cortical Network-Level Participation Coefficient as a Potential Mechanism for Transfer in Cognitive Training in AMCI.” NeuroImage. https://doi.org/10.1016/j.neuroimage.2022.119124.
Shandera-Ochsner, Anne L., Melanie J. Chandler, Dona E. Locke, Colleen T. Ball, Julia E. Crook, Vaishali S. Phatak, and Glenn E. Smith. 2021. “Comparative Effects of Physical Exercise and Other Behavioral Interventions on Functional Status Outcomes in Mild Cognitive Impairment.” Journal of the International Neuropsychological Society : JINS 27 (8): 805–12. https://doi.org/10.1017/S1355617721000485.
Phatak, Vaishali S., Glenn E. Smith, Dona Locke, Anne Shandera-Ochsner, Pamela M. Dean, Colleen Ball, Gianna Gutierrez, and Melanie J. Chandler. 2021. “Computerized Cognitive Training (CCT) versus Yoga Impact on 12 Month Post Intervention Cognitive Outcome in Individuals with Mild Cognitive Impairment.” Brain Sciences 11 (8): 988. https://doi.org/10.3390/brainsci11080988.
McMaster, Mitchell, Sarang Kim, Linda Clare, Susan J. Torres, Nicolas Cherbuin, Catherine DʼEste, and Kaarin J. Anstey. 2020. “Lifestyle Risk Factors and Cognitive Outcomes from the Multidomain Dementia Risk Reduction Randomized Controlled Trial, Body Brain Life for Cognitive Decline (BBL-CD).” Journal of the American Geriatrics Society. https://doi.org/10.1111/jgs.16762.
Lin, Feng, Ye Tao, Quanjing Chen, Mia Anthony, Zhengwu Zhang, Duje Tadin, and Kathi L. Heffner. 2020. “Processing Speed and Attention Training Modifies Autonomic Flexibility: A Mechanistic Intervention Study.” NeuroImage. https://doi.org/10.1016/j.neuroimage.2020.116730.
Czaja, Sara J., Peter Kallestrup, and Philip D. Harvey. 2020. “Evaluation of a Novel Technology-Based Program Designed to Assess and Train Everyday Skills in Older Adults.” Innovation in Aging 4 (6). https://doi.org/10.1093/geroni/igaa052.
Chen, Quanjing, Haichuan Yang, Brian Rooks, Mia Anthony, Zhengwu Zhang, Duje Tadin, Kathi L. Heffner, and Feng V. Lin. 2020. “Autonomic Flexibility Reflects Learning and Associated Neuroplasticity in Old Age.” Human Brain Mapping 41 (13): 3608–19. https://doi.org/10.1002/hbm.25034.
Valdés, Elise G., Ross Andel, Jennifer J. Lister, Alyssa Gamaldo, and Jerri D. Edwards. 2017. “Can Cognitive Speed of Processing Training Improve Everyday Functioning among Older Adults with Psychometrically Defined Mild Cognitive Impairment?” Journal of Aging and Health 31 (4): 595–610. https://doi.org/10.1177/0898264317738828.
Lin, Feng, Kathi L Heffner, Ping Ren, and Duje Tadin. 2017. “A Role of the Parasympathetic Nervous System in Cognitive Training.” Current Alzheimer Research 14 (7): 784–89. https://doi.org/10.2174/1567205014666170203095128.
Cuc, Andrea V., Dona EC Locke, Noah Duncan, Julie A. Fields, Charlene Hoffman Snyder, Sherrie Hanna, Angela Lunde, Glenn E. Smith, and Melanie Chandler. 2017. “A Pilot Randomized Trial of Two Cognitive Rehabilitation Interventions for Mild Cognitive Impairment: Caregiver Outcomes.” International Journal of Geriatric Psychiatry 32 (12): e180–87. https://doi.org/10.1002/gps.4689.
Lin, Feng, Kathi L. Heffner, Ping Ren, Madalina E. Tivarus, Judith Brasch, Ding-Geng Chen, Mark Mapstone, Anton P. Porsteinsson, and Duje Tadin. 2016. “Cognitive and Neural Effects of Vision-Based Speed-of-Processing Training in Older Adults with Amnestic Mild Cognitive Impairment: A Pilot Study.” Journal of the American Geriatrics Society 64 (6): 1293–98. https://doi.org/10.1111/jgs.14132.
Klados, Manousos A., Charis Styliadis, Christos A. Frantzidis, Evangelos Paraskevopoulos, and Panagiotis D. Bamidis. 2016. “Beta-Band Functional Connectivity Is Reorganized in Mild Cognitive Impairment after Combined Computerized Physical and Cognitive Training.” Frontiers in Neuroscience 10 (55): 1–12. https://doi.org/10.3389/fnins.2016.00055.
Styliadis, Charis, Panagiotis Kartsidis, Evangelos Paraskevopoulos, Andreas A. Ioannides, and Panagiotis D. Bamidis. 2015. “Neuroplastic Effects of Combined Computerized Physical and Cognitive Training in Elderly Individuals at Risk for Dementia: An Eloreta Controlled Study on Resting States.” Neural Plasticity 2015:e172192. https://doi.org/10.1155/2015/172192.
Gooding, Amanda L., Jimmy Choi, Joanna M. Fiszdon, Kirsten Wilkins, Paul D. Kirwin, Christopher H. van Dyck, Davangere Devanand, Morris D. Bell, and Monica Rivera Mindt. 2015. “Comparing Three Methods of Computerised Cognitive Training for Older Adults with Subclinical Cognitive Decline.” Neuropsychological Rehabilitation 26 (5–6): 810–21. https://doi.org/https://doi.org/10.1080/09602011.2015.1118389.
Bamidis, Panagiotis D., Patrick Fissler, Sokratis G. Papageorgiou, Vasiliki Zilidou, Evdokimos I. Konstantinidis, Antonis S. Billis, Evangelia Romanopoulou, et al. 2015. “Gains in Cognition through Combined Cognitive and Physical Training: The Role of Training Dosage and Severity of Neurocognitive Disorder.” Frontiers in Aging Neuroscience 7 (152): 1–15. https://doi.org/10.3389/fnagi.2015.00152.
Locke, Dona EC, Melanie Chandler Greenaway, Noah Duncan, Julie A. Fields, Andrea V. Cuc, Charlene Hoffman Snyder, Sherrie Hanna, Angela Lunde, and Glenn E. Smith. 2014. “A Patient-Centered Analysis of Enrollment and Retention in a Randomized Behavioral Trial of Two Cognitive Rehabilitation Interventions for Mild Cognitive Impairment.” The Journal of Prevention of Alzheimer’s Disease 1 (3): 143. https://doi.org/10.14283/jpad.2014.27.
Valdes, Elise G., Melissa L. O’Connor, and Jerri D. Edwards. 2012. “The Effects of Cognitive Speed of Processing Training among Older Adults with Psychometrically-Defined Mild Cognitive Impairment.” Current Alzheimer Research 9 (9): 999–1009. https://doi.org/10.2174/156720512803568984.
Rosen, A.C., L. Sugiura, J.H. Kramer, S. Whitfield-Gabrieli, and J.D. Gabrieli. 2011. “Cognitive Training Changes Hippocampal Function in Mild Cognitive Impairment: A Pilot Study.” Journal of Alzheimer’s Disease 26:349–57. https://doi.org/10.3233/JAD-2011-0009.
Barnes, Deborah E, Kristine Yaffe, Nataliya Belfor, William J Jagust, Charles DeCarli, Bruce R Reed, and Joel H Kramer. 2009. “Computer-Based Cognitive Training for Mild Cognitive Impairment: Results from a Pilot Randomized, Controlled Trial.” Alzheimer Disease and Associated Disorders 23 (3): 205–10. https://doi.org/10.1097/WAD.0b013e31819c6137.
Unverzagt, Frederick W., Linda Kasten, Kathy E. Johnson, George W. Rebok, Michael Marsiske, Kathy Mann Koepke, Jeffrey W. Elias, et al. 2007. “Effect of Memory Impairment on Training Outcomes in ACTIVE.” Journal of the International Neuropsychological Society : JINS 13 (6): 953–60. https://doi.org/10.1017/S1355617707071512.

Mild Cognitive Impairment (MCI)

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