Published Research on BrainHQ and Memory

Of all cognitive abilities, memory is one that feels particularly important to many of us. Having a sharp, effective memory makes people more confident—having memory lapses can leave them feeling insecure. To date, fifteen scientific papers—conducted by well-regarded researchers at respected universities in a variety of populations—have shown that using BrainHQ exercises can have a substantial impact on memory performance. Here are some highlights:

  • The IMPACT study—a large study from researchers at the Mayo Clinic and the University of Southern California—followed 487 people, and showed that those doing BrainHQ exercises showed an average improvement in memory more than four times larger than the control group1.
  • Multiple research papers have demonstrated “generalization” beyond trained tasks to standard memory tests. This is very important, and rarely shown for any other brain-training program. It means that the memory gains represent a real change in cognition, not just an improvement in a memory strategy.
  • A pilot imaging study showed that using BrainHQ exercises increased activity in areas of the brain associated with memory2.

Information and citations for memory-related articles

In general, these studies were conducted in cognitively healthy adults aged 65 and older, and in some cases, aged 50 and older. Remember that studies show average results, and that individual results will vary. Where published studies make reference to clinical populations, it is for informational purposes only. BrainHQ is not intended to diagnose or treat any clinical condition.
Reversal of age-related neural timing delays with training
Anderson et al. (2013)
Proceedings of the National Academy of Sciences

Study population: People 65+

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Gains in cognition through combined cognitive and physical training: the role of training dosage and severity of neurocognitive disorder
Bamidis et al. (2015)
Frontiers in Aging Neuroscience

Study population: People 65+

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The influence of perceptual training on working memory in older adults
Berry et al. (2010)
PLoS One

Study population: People 65+

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The Effects of a Computer-Based Cognitive and Physical Training Program in a Healthy and Mildly Cognitive Impaired Aging Sample
González-Palau et al. (2014)
Aging & Mental Health

Study population: People 60+

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Neural plastic effects of cognitive training on aging brain
Leung et al. (2015)
Neural Plasticity

Study population: People 65+

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Brain plasticity and functional losses in the aged: Scientific bases for a novel intervention
Mahncke et al. (2006)
Progress in Brain Research

Study population: People 65+

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Memory enhancement in healthy older adults using a brain-plasticity-based training program: A randomized, controlled study
Mahncke et al. (2006)
Proceedings of the National Academy of Sciences

Study population: People 65+

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Neural plasticity underlying visual perceptual learning in aging
Mishra et al. (2015)
Brain Research

Study population: People 65+

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Adaptive training diminishes distractibility in aging across species
Mishra et al. (2014)
Neuron

Study population: People 65+

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2 Cognitive training changes hippocampal function in mild cognitive impairment: A pilot study
Rosen et al. (2012)
Journal of Alzheimer’s Disease

Study population: People 65+

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A combination of physical activity and computerized brain training improves verbal memory and increases cerebral glucose metabolism in the elderly
Shah et al. (2014)
Translational Psychiatry

Study population: People 65+

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1A cognitive training program based on principles of brain plasticity: results from the improvements in memory with plasticity-based adaptive cognitive training (IMPACT) study
Smith et al. (2009)
Journal of the American Geriatric’s Society

Study population: People 65+

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Cognitive function in elderly can be ameliorated by training in temporal information processing
Szelag et al. (2012)
Restorative Neurology and Neuroscience

Study population: People 65+

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Improvement in memory with plasticity-based adaptive cognitive training: Results of the 3-month follow-up
Zelinski et al. (2011)
Journal of the American Geriatric’s Society

Study population: People 65+

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Evaluating the relationship between change in performance on training tasks and on untrained outcomes
Zelinski et al. (2014)
Frontiers in Human Neuroscience

Study population: People 65+

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