Posit Science collaborated with Mayo Clinic on the 487-person IMPACT Study, which was the first randomized controlled trial to show generalization of brain training to gains in standard measures of speed of processing speed, attention and memory, and everyday cognitive activities. We also supply the brain fitness exercises used in the HABIT (Healthy Action to Benefit Independence & Thinking) program created at Mayo to help patients with amnestic Mild Cognitive Impairment and early stage Alzheimer’s.